Gregory J Morton Selected Research

Fibroblast Growth Factor 1 (FGF-1)

1/2022	Combined micro-osmotic pump infusion and intracerebroventricular injection to study FGF1 signaling pathways in the mouse brain.
9/2021	Role of hypothalamic MAPK/ERK signaling and central action of FGF1 in diabetes remission.
10/2020	Hypothalamic perineuronal net assembly is required for sustained diabetes remission induced by fibroblast growth factor 1 in rats.
1/2020	Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission.
1/2019	Peripheral Mechanisms Mediating the Sustained Antidiabetic Action of FGF1 in the Brain.
1/2019	The Hypothalamic Arcuate Nucleus-Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1.
1/2016	Central injection of fibroblast growth factor 1 induces sustained remission of diabetic hyperglycemia in rodents.

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Gregory J Morton Research Topics

Disease

17	Obesity 01/2019 - 05/2003
17	Insulin Resistance 01/2019 - 12/2005
16	Hyperglycemia 01/2022 - 02/2011
13	Body Weight (Weight, Body) 01/2019 - 05/2003
9	Weight Loss (Weight Reduction) 10/2017 - 05/2007
8	Type 2 Diabetes Mellitus (MODY) 01/2022 - 08/2011
8	Weight Gain 01/2017 - 05/2007
7	AIDS-Related Complex (ARC) 01/2022 - 05/2003
7	Hypoglycemia (Reactive Hypoglycemia) 01/2020 - 07/2004
7	Inflammation (Inflammations) 01/2017 - 11/2008
4	Diabetes Mellitus 01/2018 - 02/2011
3	Hyperphagia (Overeating) 12/2020 - 10/2004
3	Ketosis 01/2018 - 11/2014
3	Glucose Intolerance 01/2017 - 11/2013
3	Anorexia 08/2014 - 05/2007
2	Metabolic Diseases (Metabolic Disease) 12/2014 - 09/2010
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 09/2013 - 08/2011
1	Hyperthermia 01/2019
1	Androgen-Insensitivity Syndrome (Testicular Feminization) 05/2018
1	Diarrhea 03/2015
1	Nausea 03/2015
1	Atherosclerosis 12/2014
1	Vitamin D Deficiency 04/2012
1	Non-alcoholic Fatty Liver Disease 04/2012
1	Overweight 04/2012

Drug/Important Bio-Agent (IBA)

23	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 07/2004
19	LeptinIBA 01/2018 - 05/2003
17	Insulin (Novolin)FDA Link 01/2020 - 07/2004
7	Fibroblast Growth Factor 1 (FGF-1)IBA 01/2022 - 01/2016
7	Glucagon (Glukagon)FDA Link 12/2018 - 07/2004
7	Leptin ReceptorsIBA 09/2013 - 05/2003
5	Hypoglycemic Agents (Hypoglycemics)IBA 01/2019 - 11/2013
5	Streptozocin (Streptozotocin)FDA Link 01/2018 - 10/2004
4	Peptides (Polypeptides)IBA 01/2022 - 07/2004
4	Blood Glucose (Blood Sugar)IBA 01/2019 - 07/2010
4	Oxytocin (Pitocin)FDA LinkGeneric 10/2017 - 01/2012
4	Messenger RNA (mRNA)IBA 09/2005 - 05/2003
3	EnzymesIBA 01/2019 - 12/2005
3	CorticosteroneIBA 12/2018 - 07/2004
3	MelanocortinsIBA 01/2017 - 04/2004
3	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 01/2017 - 05/2003
3	LipidsIBA 12/2014 - 05/2009
2	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 01/2019 - 08/2015
2	pyrrolidonyl-beta-naphthylamideIBA 01/2018 - 04/2016
2	Protein Isoforms (Isoforms)IBA 01/2017 - 05/2003
2	Steroidogenic Factor 1IBA 04/2016 - 09/2013
2	fibroblast growth factor 21IBA 08/2015 - 07/2010
2	Lipase (Acid Lipase)FDA Link 04/2015 - 03/2010
2	Hormones (Hormone)IBA 07/2010 - 10/2004
2	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 07/2009 - 12/2005
2	Neuropeptide YIBA 07/2004 - 05/2003
1	Chondroitin Sulfates (Chondroitin Sulfate)IBA 10/2020
1	GlycosaminoglycansIBA 10/2020
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 01/2019
1	GlucokinaseIBA 01/2019
1	AdipokinesIBA 01/2017
1	PKC-3 proteinIBA 01/2017
1	Protein Kinase CIBA 01/2017
1	Conjugated Linoleic AcidsIBA 01/2017
1	Transcription Factors (Transcription Factor)IBA 04/2016
1	cholecystokinin 8IBA 04/2016
1	GlucocorticoidsIBA 11/2015
1	LigandsIBA 08/2015
1	PD 173074IBA 08/2015
1	Liraglutide FDA Link 07/2015
1	Serine (L-Serine)FDA Link 04/2015
1	Alanine (L-Alanine)FDA Link 04/2015
1	FructoseIBA 03/2015
1	Biological ProductsIBA 12/2014
1	Melanocortin Receptors (Melanocortin Receptor)IBA 11/2014
1	Glucagon-Like Peptide 1 (GLP 1)IBA 08/2014
1	Estrogens (Estrogen)FDA Link 04/2014
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 05/2013
1	GC 1 compoundIBA 04/2013
1	Thyroid HormonesIBA 04/2013
1	EndotoxinsIBA 04/2012
1	High Fructose Corn SyrupIBA 04/2012
1	Vitamin D FDA LinkGeneric 04/2012
1	ResistinIBA 04/2012
1	nasIBA 04/2012
1	Toll-Like Receptors (Toll-Like Receptor)IBA 04/2012
1	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 11/2011
1	vasodilator-stimulated phosphoproteinIBA 11/2011
1	Type 5 Cyclic Nucleotide PhosphodiesterasesIBA 11/2011
1	Triglycerides (Triacylglycerol)IBA 08/2011
1	Sodium Glutamate (Accent)IBA 03/2011
1	N(epsilon)-(carboxymethyl)hydroxylysineIBA 03/2011
1	10- methoxy- 2- methyl- 7H- pyrido(4,3- c)carbazolium (MMPC)IBA 09/2010
1	CytokinesIBA 07/2010
1	PS1145IBA 07/2010
1	Interleukin-4 (Interleukin 4)IBA 07/2010
1	TOR Serine-Threonine KinasesIBA 07/2009
1	Insulin ReceptorIBA 07/2009
1	Janus KinasesIBA 07/2009
1	Sirolimus (Rapamycin)FDA Link 07/2009

Therapy/Procedure

2	Therapeutics 01/2016 - 04/2014
2	Intraventricular Infusions 07/2010 - 09/2005
1	Caloric Restriction 01/2017
1	Injections 03/2015
1	Vagotomy 10/2009